It comes on the heels of several other classic movies that have recently been adapted into successful video games, including The Godfather and Scarface.
'Iconic'
"We noticed we did well on Scarface and were alert for new opportunities to turn iconic film products into games in a way that is a new manifestation of the franchise," Vivendi Games chief executive Bruce Hack said.
"Ghostbusters is unquestionably among the small number of movies in that class."
The new game will be set in the early 1990s after the events of Ghostbusters II.
Some supporting cast members have even signed up to participate, including Annie Potts who played the ghost-busting team's receptionist, Janine.
Several Ghostbusters games were released around the time of the two movies, and one in the past decade was tied to the animated series, Extreme Ghostbusters.
